In 1977, college graduates Harry Burns (Billy Crystal) and Sally Albright (Meg Ryan) share a contentious car ride from Chicago to New York, during which they argue about whether men and women can ever truly be strictly platonic friends. Ten years later, Harry and Sally meet again at a bookstore, and in the company of their respective best friends, Jess (Bruno Kirby) and Marie (Carrie Fisher), attempt to stay friends without sex becoming an issue between them.
Tom Hanks and Meg Ryan star in Nora Ephron's wonderfully romantic comedy about two people drawn together by destiny. Hanks stars as Sam Baldwin, a widowed father who, thanks to the wiles of his worried son, becomes a reluctant guest on a radio call-in show. He's an instant hit with thousands of female listeners who deluge his Seattle home with letters of comfort. Meanwhile, inspired in equal parts by Sam's story and by classic Hollywood romance, writer Annie Reed (Ryan) becomes convinced that it's her destiny to meet Sam. There are just two problems: Annie's engaged to someone else and Sam doesn't know yet that they're made for each other. Co-starring Rosie O'Donnell, Rita Wilson and Rob Riener.